pentobarbital will minimize the level or influence of netupitant/palonosetron by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Netupitant is especially metabolized by CYP3A4; stay away from use in clients who're chronically applying a powerful CYP3A4 inducerBarbiturates are prescription drugs that indu… Read More